Central and Northern Florida chapter was incorporated in 1994. After two years of hard work on the part of the founding Board of Directors, a provisional charter was granted to the Make-A-Wish Foundation of Central Florida. In 2001 the chapter grew to include an additional 36 counties of Northern Florida and became the Make-A-Wish Foundation of Central and Northern Florida. The chapter merged with the former Sarasota/Tampa Bay Chapter (now the Suncoast region) in September 2006.
Make-A-Wish Central and Northern Florida now serves 54 counties including the Central, Northern, Space Coast and Suncoast regions of Florida. The staff works in Maitland and two regional offices in Tampa and Sarasota.